Scientists discover a new way to disarm a deadly protein that also appears in cancers of the lung, breast and colon.

UC San Francisco researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.

The new molecule permanently modifies a wily cancer-causing mutation, called K-Ras G12D, that is responsible for nearly half of all pancreatic cancer cases and appears in some forms of lung, breast and colon cancer.

New Cleveland Clinic-led research points to sildenafil (Viagra) as a potential treatment for Alzheimer's disease. The study provides evidence from computational models, insurance claims data and observations from brain cells in Alzheimer's patients.

Sildenafil is the main component of drugs used to treat erectile dysfunction (Viagra) and pulmonary arterial hypertension (Revatio).

Amgen Pushes Obesity Drug MariTide Forward, Reports 22% Q1 Revenue Growth 5/3/2024

Boehringer, Walgreens Team Up for Obesity Trial as Weight-Loss Drug Race Heats Up 5/3/2024

FDA’s Accelerated Approval of Sarepta DMD Gene Therapy Comes Under Fire 5/3/2024

BioSpace Heads to #ASGCT, Along with Thousands in Cell and Gene Therapy 5/3/2024

Novo Nordisk’s Wegovy Pricing Drops as Competition Heats Up with Eli Lilly 5/3/2024

Novartis today presented new data that continue to support the clinical benefits of Zolgensma® (onasemnogene abeparvovec), the only one-time gene therapy for the treatment of spinal muscular atrophy (SMA). Final data from the SMART study highlight the safety and efficacy profile of Zolgensma in children with SMA weighing ≥ 8.5 kg to ≤ 21 kg, with a mean age of 4.69 years, most of whom (21/24, 87.5%) had discontinued use of another disease modifying therapy at the time of treatment.

Biden, Sanders Target Drug Prices at White House Event 4/3/2024

Genmab Leans into Hot ADC Space with $1.8B ProfoundBio Acquisition 4/3/2024

Vanda Gets FDA Approval for Fanapt Antipsychotic, Expands into Bipolar Disorder 4/3/2024

Diagonal Therapeutics Nets $128M for New Approach to Agonist Antibodies 4/3/2024

Four Doses of Lilly’s Mounjaro Will Be in Short Supply Through April 2024: FDA 4/3/2024

Did WuXi Make a Whoopsie? US-China R&D Relations in Limbo 4/3/2024

Acorda Joins Growing Group of Biotechs Filing for Bankruptcy, Divests Assets to Merz 4/3/2024

Chinese ADC Investment Boom in Question With China-U.S. R&D Relations in Flux 4/3/2024

Opinion: Slow Down on IRA Expansions, Research Possible Outcomes 4/3/2024

Flush With New $150M Investment, Avenzo Pursues Licensing Strategy 4/3/2024

C-Suite Shuffle: Lonza Hires New CEO 4/3/2024

Cleveland Clinic researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi's sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.